NASH and Hepatic Fibrosis

Non- Alcoholic Hepatic Fibrosis

❖ ~16.5M patients in US with NASH

❖ 3M with liver cirrhosis due to NASH

❖ No curative Rx to date

❖ Leading cause for liver transplantation

US ARDS market size $2.9B annually

❖ NASH growing at ~3% per year, large unmet need

❖ Market Opportunity

No FDA-Approved NASH-Specific Therapy

Saroglitazar (India)- PPAR agonist, insulin sensitizer

❖ eNAMPT-Neutralizing ALT-100 mAb as a Novel Therapy for NASH Fibrosis and HCC

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News and Press Releases Related to NASH and Hepatic Fibrosis

Learn More about NASH and Hepatic Fibrosis

Learn More About ALT-100 mAb